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Dpyd
5-FU
MOA
Thymidylate
Synthase
5-FU Mechanism
of Action
5-Fluorouracil Mechanism
of Action
5-
Fdump
5-FU
Chemotherapy
Leucovorin Mechanism
of Action
5-FU to
FdUMP
5-
Fluoro
De Novo
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Floxuridine
FdUMP
in a Bubble
Base Excision
Repair
Xeloda Mechanism
of Action
Ejpt
Dump
Fluorouracil
Synthesis
5-FU
Metabolism
5-
FOA
Arachidonic
Acid Pathway
De Novo Pyrimidine
Synthesis
Fluoxiuridine to
FdUMP
Thymidine
Kinase 1
FdUMP
and Folate Cofactor
Fudr and
5-FU
Dump
Optimization
HCT116
5-FU
5-FU
Activation
Orotate
Monophosphate
Vuv
Dump
Eucovorin for Capecitabine
FdUMP
FdUMP
and Methylenetetrahydrofolate
Methylene Thf Binding to
FdUMP
Downjoad
FDM
FRD
Ddmp
Carbamoyl Phosphate
Synthetase I
CDF
Dump
Deoxyuridine
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5-FU
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Uridine
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5
Fluorodeoxyuridine
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RNA
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How to Decode
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Figure 1 from Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase ...
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Simplified schematic of the intracellular conversion of 5-F…
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The analogues of dUMP and FdUMP i…
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The analogues of dUMP and FdUMP included in FEP simulations. | Downloa…
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Chemical structure of FdUMP[10], evaluate…
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