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生物通
13 天
全长 16S rRNA 测序:肥胖儿童代谢相关脂肪性肝病的肠道微生物组新探索
传统的短读长测序,如 V3 - V4 测序,虽然在微生物研究中被广泛应用,但存在分类学模糊的问题,难以区分一些序列相似性高的物种。而全长 16S(FL16S)rRNA 测序技术的出现,带来了更高的分类学分辨率,不过它在临床肠道微生物组分析中的优势,还缺乏与短读 ...
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