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mRNAm6A通过 5’ UTR 区 H3K4me3 修饰调控基因表达的新发现
其中, m6A 作为真核生物中常见且保守的 RNA 修饰,一直是科研人员关注的焦点。以往的研究大多聚焦于 m6A 在 3’非翻译区(3’ UTR)的功能,对 5’非翻译区(5’ UTR)的 m6A 修饰却知之甚少,它与组蛋白修饰之间的关系更是迷雾重重。这些未知就像一道道谜题 ...
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