Weight gain should be monitored. A total serum albumin level, which is normally between 3.5 and 5.0 g/dL, may reveal deficiencies in protein intake. Edema secondary to renal disease can be ...

Cases of methadone causing edema and weight gain have been reported with both tablets and the liquid formulation. A 31-year-old man taking methadone 500 mg twice daily as part of a detoxification ...