The shape of a protein determines what it can interact with, just like the shape of a key determines which locks it can operate. Most of the proteins in your body can be grouped into four ...

Federal science agencies have renewed and increased funding for a world-renowned digital archive of protein structures housed ...

Today, however, most cryo-EM studies resolve protein structures only to about three or four angstroms, leaving a picture that’s too blurry for structure-based drug design. And despite AlphaFold ...