ACR（又称尿ACR）为尿微量白蛋白/尿肌酐比值，其主要检测人体尿中蛋白质与肌酐的排出情况，是反映人体肾功能的一项敏感指标。正常人体排出的尿液中一般不含有或仅含微量的白蛋白。当人体肾脏的肾小球基底膜受到损伤或缺陷时，白蛋白便会从肾小球漏出，出现在尿液中。正常尿液中白蛋白含量不超过30mg/24h，临床上将尿液中白蛋白含量在30~300mg/24h范围内的称为尿微量白蛋白。

研究人员进行了一项回顾性研究，他们从 2012 年 2 月到 2023 年 10 月，收集了中山大学附属第一医院收治的 178 例妊娠期 SLE 患者的临床资料。这些患者都符合 1997 年美国风湿病学会（ACR）制定的 SLE 分类标准。研究人员根据血小板计数，把患者分为血小板减少组 ...

I 型干扰素 （IFN-I） 信号在系统性红斑狼疮 （SLE） 发病过程里的作用已得到充分证实。而目前发现的单基因系统性红斑狼疮样疾病（monogenic systemic lupus erythematosus ）的主流是自身炎症I ...

ACR 2024 highlighted a pivotal moment in autoimmune ... exercising his expertise in cutting-edge developments across autoimmune diseases like SLE and cell therapies such as CAR-Ts.

Recurrent pericarditis occurred in one fifth of patients with systemic lupus erythematosus (SLE), with higher recurrence rates observed in younger patients and those receiving oral prednisone therapy.

This work will impact patient care as it will increase the interpretability of the scores of the ACR-NB and improve the early identification of CI in SLE patients. This could lead to extraordinary ...

Patients receiving ICIs were associated with a greater risk of developing RA, but lower risks for SLE and SSc.