Particularly affected, for example, are patients with a special form of blood cancer, acute myeloid leukemia with complex karyotype (CK-AML). The chromosomes of these leukemia cells are in a state ...

in difficult-to-treat TP53-mutated/CK AML and FLT3-wildtype AML patients, including a measurable residual disease (MRD) negative remission Dosing of initial 40 mg cohort complete; no prolonged ...