研究人员针对 ARID1A 缺陷型卵巢透明细胞癌(OCCC)治疗难题,研究靶向 USP8,发现其可诱导合成致死,有望用于精准治疗。
The Institute of Cancer Research, London, is seeking a partner to continue the development of ARID1A and other BAF-complex genes as cancer biomarkers for predicting sensitivity to ATRi. More about ...
NXP800 Phase 1b study in patients with platinum resistant, ARID1a-mutated ovarian cancer is ongoing; Orphan Drug Designation granted by the U.S. FDA. Updated Phase 1b results anticipated in Q2 2025 ...
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