"Our findings reveal that the basal ganglia—a brain circuit regulating adaptive behavior and motor functions—is affected in autism, with disruptions in how dopamine and acetylcholine work ...

Researchers at Karolinska Institutet have uncovered new insights into the mechanisms underlying autism spectrum disorder (ASD). The study, recently published in Cell Reports, explores how changes in ...

A pathway once considered fundamental in Alzheimer’s disease is being studied intensely again, and may soon result in safer, ...

IT has been suggested 1 that the vesicle-like structures inside the axon near the neuromuscular junction contain acetylcholine, but that “it would be practically impossible to pack 10 5 ...

The pharmacotherapy of schizophrenia is currently dominated by atypical antipsychotics that primarily target dopaminergic signalling, the dysregulation of which has long been considered to have a ...

In this figure extracted from the research study, staining of proteins highlights various cell type makers: neurons overall (cyan), and cells specifically involved with neurotransmitters dopamine ...

Acetylcholine is a neurotransmitter that helps to activate muscles and causes them to contract. The discovery of lynx1 had potential clinical importance since nicotine is known to increase the level ...