Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the ...

Every enzyme has a place in which the molecule fits exactly. This is known as the active site. The active site of the catalase allows the hydrogen peroxide molecule to fit exactly. You could say ...

Researchers have used artificial intelligence (AI) to design brand-new enzymes that can go through multi-step reactions, a ...

What are enzymes and how they operate? Enzymes are the molecules in our bodies that facilitate reactions. They perform this function at their active site, which is like their ‘mouth’.

Synthetic proteins that promote multi-step catalysis have previously proven challenging to engineer. But the team behind this ...

leading to an increase in enzyme activity. This means the active site loses its important shape and can no longer form enzyme-substrate complexes, leading to a decrease in enzyme activity.

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...

Herschlag and Du broke down enzyme catalysis to the individual energetic contributions at the precise place where enzyme and ...

Since enzymes are quite efficient biocatalysts active under mild conditions, they are expected to be applied to varieties of environmentally benign chemical processes realized in the next generation.