Acyclovir gets converted to acyclovir triphosphate ... Renal impairment: reduce dose (see full labeling); give another dose after hemodialysis. Nausea, vomiting, headache, CNS disturbances ...

Acyclovir (as sodium ... All: max 20mg/kg every 8 hours. Obese: dose based on ideal body weight. Renal impairment: CrCl 25–50mL/min: give dose every 12 hours; CrCl 10–25mL/min: give dose ...

In a 10-week study of three times daily oral acyclovir against placebo ... The risk of systemic side effects is greater in infants than in adults due to increased percutaneous drug absorption ...