2025年3月18日,中山大学的研究团队在期刊《Cell Reports》上发表了题为“AGO2 mediates immunotherapy failure via suppressing tumor IFN-gamma response-dependent CD8+ T cell ...
同时,过表达这些 circRNA 还会使 HCMECs 中炎症相关基因(如 IL-1β、IL-6、VCAM-1 ... RNA Pull-Down 实验和双荧光素酶报告基因实验证实了两者的结合,RNA 结合蛋白免疫沉淀(RIP)实验表明这种结合由 AGO2 介导。转染 miR-103a-3p 可降低 circSARS-CV2-N1368 的表达水平,反之亦然。
Taiwanese scientists have discovered a new way to synthesize circular RNA (circRNA), which could be applied to vaccine development, the National Institute of Infectious Disease and Vaccinology told a ...