然而，肿瘤细胞能够通过多种机制逃避 IFN-γ 介导的免疫激活，导致免疫治疗失败。 Argonaute 2（AGO2）是 Argonaute 家族的关键成员，作为微小 RNA（miRNA）传感器，可对 miRNA 库的动态变化迅速做出反应，并靶向下游 mRNA 发挥多种作用。AGO2 在肿瘤免疫治疗中的作用 ...

This study also reveals that endonuclease-competent Argonaute-2 (AGO2) cleaves precursor miRNAs (pre-miRNAs) to produce a new processing intermediate. ...Argonaute proteins post-transcriptionally ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...