在微观的细胞宇宙中,一个名为PTEN(Phosphatase and tensin homolog)的蛋白质如同精密的分子刹车,时刻调控着细胞增殖与存亡。这个仅有403个氨基酸的 ...
为探究乳腺癌(BC)进展中 HR 状态转变机制,研究人员对 ER + /HER2? 患者研究,发现 PTEN 突变与之有关。 在乳腺癌(Breast Cancer,BC)的发展进程中,激素受体(Hormone Receptor,HR)的状态可能并不稳定,大约 20 - 30% 的乳腺癌患者在复发时会出现这种状态变化。
为明确 PTEN 错构瘤肿瘤综合征(PHTS)中非成分癌症(NCC)情况,研究人员开展相关研究,发现其 NCC 谱,具重要意义。 PTEN 错构瘤肿瘤综合征(PTEN hamartoma tumor syndrome,PHTS)听起来或许有些陌生,但它却与多种癌症的发生息息相关。PHTS 是一类由致病的种系 PTEN ...
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Mutations in PTEN are linked to a variety of conditions, including autism, epilepsy, and cancer. Dynamics of mEGFP-PTEN-sREACH activity following TBB application in HEK293. A movie showing changes ...
PTEN remains capable of generating 15% free cash ... The anticipation for an eventual recovery has grown even larger with the introduction of AI data centers potentially driving up the need ...