Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

In a nutshell A common desert plant called Artemisia herba-alba contains compounds that can effectively kill colorectal cancer cells in laboratory tests while appearing to leave healthy cells unharmed ...

The new study adds to growing evidence that measuring activated proteins is key to cancer therapy selection. Golden, CO, Feb.

Although inhibitors targeting elements of the PI3K/AKT/mTOR pathway are promising approaches for leukemia therapy, there is an increasing consensus that these strategies will also have limited ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...

Ignite Proteomics announces the publication of a significant study in the British Journal of Cancer titled “Functional activation of the ...

Additionally, it blocked the PI3K/AKT/mTOR pathway, which plays a major role in cancer development,” adds Dr. Bou Malhab. “The current study underscores the extract's selective cytotoxicity against ...

【导读】帕博西尼（Palbociclib）是一种CDK4/6抑制剂，在治疗HR+乳腺癌中发挥着至关重要的作用。然而，palbociclib的耐药性是一个值得进一步研究的重大问题。团队的研究发现，TMEM45A是palbociclib耐药性的潜在驱动因 ...

Anxiety disorders, characterized by an excessive apprehension about real or perceived threats and dysfunctional behaviors aimed at avoiding these threats, are among the most common mental health ...

Additionally, it blocked the PI3K/AKT/mTOR pathway, which plays a major role in cancer development," adds Dr. Bou Malhab. "The current study underscores the extract's selective cytotoxicity ...