Amyloid precursor protein (APP ... Here we describe the 1.8 Å resolution crystal structure of the N-terminal, heparin-binding domain of APP (residues 28–123), which is responsible, among ...

To determine the three-dimensional structure of small proteins such ... of other small and unstable proteins—including the amyloid-beta peptide that builds up in the brain in Alzheimer's disease.

Protein accumulations do important work in the human body, but something can go wrong and proliferate in those aggregates, ...