Angelman syndrome is caused by a large deletion of the region of the maternal chromosome that contains UBE3A, or by a DNA sequence change (mutation) in the UBE3A gene inherited from the mother.

For the first time, Colin Farrell has opened up his home and talked in-depth about life with his son James, who has Angelman ...

We each get two copies of every gene - one copy from each of our parents. But what happens when one of these genes has been "turned off", or imprinted, and the remaining gene is defective?

each focusing on different mechanisms to address Angelman syndrome. There was a lack of interest among standard pharmaceutical companies, so FAST took a venture philanthropy approach to clinical ...