that have critical functionsin maintaining the shape and apical-basal polarity of epithelial cells. Figure 1: The domains and junctions of epithelial cells. Adherens junctions (AJ)contain the most ...

Intestinal organoids that are classically grown in 3-D matrices are cystic, which means that they have a monolayer of epithelial cells with fluid inside. The cells interact with the matrix on the ...

2 Additionally, they employ organoids to investigate development, drug response and toxicity, and interactions between epithelial cells and host microbiota or pathogens. Traditional methods produce ...

Cells within epithelial monolayers exert forces ... promotes a shift in the extrusion mode from the apical to the basal side, influencing the fate of the extruded cells. "Our work demonstrates ...