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14 天
YY1 介导的 DUXAP8 通过调控 DEPDC1 表达促进肝癌进展:潜在的治疗新靶点
YY1 促进 DUXAP8 表达:利用生物信息学工具预测并通过实验证实,转录因子 YY1 可与 DUXAP8 启动子结合,促进其表达。当抑制 YY1 表达时,DUXAP8 水平显著下降;反之,过表达 YY1 则会使 DUXAP8 表达上调。 DUXAP8 作为 miR - 7 - 5p 的海绵:经数据库预测和实验验证 ...
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