In the presence of HIT, the use of LMWHs or initiation of warfarin without additional effective anticoagulation is not recommended. Argatroban and lepirudin, two direct thrombin inhibitors (DTIs ...

There is no known reversal agent for argatroban. The package insert recommends "symptomatic and supportive therapy." [5] With FFP, the coagulation parameters returned to the baseline level of ...