A man suspected of setting fire to several Tesla vehicles at a repair facility in Las Vegas last week has been arrested, ...
They also activate the β-arrestin signalling pathway, which is associated with side effects and tolerance. Rangari et al. therefore set out to rationally design CB1 agonists that are restricted ...
This is because different ligands will stabilize the GPCR in different conformations, and that determines which of the transducers — a G protein or an arrestin — will bind to the receptor most ...