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生物通
26 天
非洲猪瘟病毒关键毒力基因 MGF_360-4L 的探秘之旅:免疫逃逸机制与 ...
ASFV 是一种大型双链 DNA 病毒,其基因组庞大且复杂 ... MGF_360-4L 影响 MDA5 与 MAVS 的相互作用及 ISGylation 修饰 在病毒感染过程中,MDA5 识别病毒产生的 dsRNA 后,会招募 MAVS 传递信号并激活 IFN 信号通路。同时,MDA5 还可通过 ISG15 介导的 ISGylation 修饰激活,发挥 ...
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