Nature29 天
Self-eating and self-killing: crosstalk between autophagy and apoptosis
Autophagy and apoptosis may be triggered by ... Among the initial steps of vesicle nucleation is the activation of mammalian Vps34, a class III phosphatidylinositol 3-kinase (PI3K), to generate ...
News Medical on MSN5 个月
New insights into the mechanism of autophagy activation
The ULK1 complex is known to translocate from the cytoplasm to the endoplasmic reticulum membrane, where autophagosomes are ...
来自MSN21 天
Boosting autophagy in eggs may reduce DNA damage and reproductive complications
More information: Fei Sun et al, Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation, Nature Communications (2024). DOI: 10.1038/s41467-024-53559-w ...
Medical Xpress29 天
Light-activated compound offers hope for overcoming drug resistance in cancer treatment
To combat this autophagy, the research team designed a ... Analysis revealed that the compound, upon light activation, disrupted the lysosomal membrane and prevented its fusion with autophagosomes ...
Science Daily21 天
How mitochondria drive autophagy
Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy. Autophagy , 2024; 1 DOI: 10.1080/15548627.2024.2440843 Cite This Page : ...