"We have now been able to show that the receptors must bind weakly to the material to be disposed of for autophagy to start," explains Kraft. "If they bind too strongly, the process is not triggered." ...

In order for the degradation of cellular components through autophagy to occur, they must first be recognised as waste. This is done by receptor and other adapter molecules. However, it was ...

Weak molecular interactions essential for autophagy to begin In order for the degradation of cellular components through autophagy to occur, they must first be recognised as waste. This is done by ...

“We have now been able to show that the receptors must bind weakly to the material to be disposed of for autophagy to start,” explains Kraft. “If they bind too strongly, the process is not ...

Researchers from AUTOTAC Bio Inc. and affiliated organizations presented preclinical data for ATC-324, a novel autophagy-targeting chimera (AUTOTAC) designed to induce androgen receptor (AR) ...

BM mesenchymal cells were similarly analyzed using markers like CD200 and vascular endothelial growth factor receptor (VEGFR ... eNOS, and autophagy. Conditional deletion of CD200 or the cilia ...

We also are testing our hypothesis that the splicing factors and their mediated events are essential for endometrial function pivotal to successful implantation. Autophagy in Uterine Development and ...