而 B7-H 家族作为免疫调节网络的重要组成部分，包括 B7-H2（ICOSL）、B7-H3、B7-H4、B7-H5（VISTA）、B7-H6 和 B7-H7（HHLA2）等成员，在肿瘤免疫调节中发挥着多样且关键的作用，为癌症免疫治疗带来了新的契机。 B7-H 家族：肿瘤免疫与治疗的关键调节因子 B7/CD28 超家族 ...

A retrospective study showed that either folate receptor alpha or B7-H4 was expressed in more than 80% of endometrial cancers ...

Puxitatug samrotecan (P-Sam), an investigational antibody-drug conjugate (ADC) targeting B7-H4-expressing tumors, showed ...

GSK'277 was the company's second licensed ADC from Hansoh, coming after it secured rights to HS-20089, a B7-H4 targeted ADC with potential as a triple-negative breast cancer treatment, for $85 ...

AstraZeneca (AZN) presented data at SGO 2025 Meeting on Women’s Cancer from the Phase 1/2a BLUESTAR trial evaluating puxitatug samrotecan, a B7-H4 ADC targeting TOPO1, which demonstrated ...