Importantly, Ding et al. indicated that exercise seemed to facilitate tPA activation, allowing tPA to assist in attaching proBDNF to mBDNF. This attachment process was also found to initiate synaptic ...

Together, these studies provide a promising new strategy to generate small-molecule mimetics of BDNF that might unlock the potential of NTRK2 activation to treat a broad range of neurological ...

Exercise influences levels of neurotrophins, proteins that promote the proliferation of neurons and support their function. Physical activity enhances DNA demethylation in the promoter region of the ...

In the latest study, BDNF was found to have a role as a signal for the body to refuel energy sources in muscles after ...

Exercise activates hope molecules, beneficial biochemicals that improve mood and reduce stress. Myokines, like BDNF, play a key ... making you feel happier. How to activate these hope molecules?

An emerging body of multidisciplinary literature has documented the beneficial influence of physical activity engendered through aerobic exercise on selective aspects of brain function.