It offers Azeliragon, TTP399, TTP273, HPP593, HPP737, and the Nrf2/Bach1 program. The company was founded on April 2, 2015 and is headquartered in High Point, NC.

FANCJ, also known as BACH1 or BRIP1, was identified as a direct BRCA1-BRCT interacting protein and functions in DNA repair and checkpoint control. Bi-allelic inheritance of mutations in FANCJ ...