A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

Fu and colleagues used Vibrio cholerae bacteria as a model for studying the plasmid defense system known as DdmDE, consisting of proteins called DdmD and DdmE, using cryo-electron microscopy to ...

Outer membrane protein TraT protects bacteria from secondary F plasmid conjugation. Here, the authors report cryo-EM structure of decameric cork-like TraT and its evolutionary history as a ...

Most methods require delivery of the re-sensitized system by conjugation; the vector is carried by a non-virulent lab strain bacteria that is supposed to go and share the vector/plasmid through ...