Basophils also release IL-4, so Vöhringer wondered if basophils might act coordinately with Th2 cells. He started by trying to conditionally remove a protease that was specific to basophils. Luckily, ...

we established basophil-specific TTP-knockout mice and evaluated the severity of allergic inflammation using an oxazolone-induced atopic dermatitis model." The study revealed that TTP plays a ...