来自MSN1 个月
Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments
β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin ... health complications. Iron overload is a common and severe complication ...
Nature5 年
THE POTENTIAL OF TIN-PROTOPORPHYRIN AS AN ADJUVENT THERAPY FOR IRON OVERLOAD IN THALASSEMIA ...
Despite present therapies of hypertransfusion and chelation of iron with ... patients with thalassemia major continue to succumb in their early to mid twenties to fatal iron overload, especially ...
University of Bristol1 年
Immortalised B-thalassemia and CDA IV erythroid lines
Beta-thalassemia is a blood disorder resulting in the reduction of haemoglobin production ... CDA IV is a severe form of anaemia where patients present with splenomegaly, iron overload and a number of ...