此外,Uncalled4 还能训练包含人工修饰的孔模型,如在酿酒酵母(Saccharomyces cerevisiae)DNA 中引入 BrdU 的模型训练,且 Uncalled4 训练的模型在分类 BrdU 修饰的读取方面表现更优。 比较 RNA 修饰检测:在 RNA 修饰检测实验中,研究人员使用 Uncalled4、Nanopolish 和 Tombo 对 ...
Liver and duodenum were frozen in OCT buffer on dry ice. We used duodenum as a positive control for DNA synthesis (that is, BrdU incorporation). We mounted sections (7 μm) of the tissue onto ...