HSAF has demonstrated broad-spectrum antifungal activity, but its mode of action was not well understood until recent studies shed light on its effects on fungal pathogens like Neurospora crassa.

Raad II, Boktour MR, Hanna HA, Kontoyiannis DP, Hachem RY. Posaconazole compared to amphotericin B lipid formulations alone or in combination with itraconazole as salvage therapy for invasive ...

Hordedanes act as a broad-spectrum antifungal agent. Above all, they inhibit spore germination and the growth of some harmful and also beneficial fungal species. Surprisingly, however, an ...

Anti-Fungal Therapy Market. The global anti-fungal therapy market is set to experience significant growth, with a projected ...

These newer drugs have a broader antifungal spectrum with activity against resistant fungi. Itraconazole is a fungistatic oral agent which slows fungal cell growth by inhibiting cytochrome P450 ...

The Biomedical Advanced Research and Development Authority (BARDA) announced last week that it has awarded $29 million to Swiss drugmaker Basilea Pharmaceutica to develop two first-in-class antifungal ...

BACKGROUND In a retrospective study the value of bronchoalveolar lavage (BAL) in the diagnosis of pneumonia was investigated in 95 immunocompromised patients suffering from haematological disorders ...

Prompt and efficient treatment of the IFI is essential for the survival of the patient. This article examines three distinct clinical situations where liposomal amphotericin B, a broad-spectrum ...