“I believe we've hit not only the cell of origin for lung adenocarcinoma, but also the pathway of origin,” says Kadara. This cancer originates in the epithelial cells that line the lung’s ...

The study characterizes the lung cancer tumor microenvironment, linking cellular compositions to immunotherapy resistance and ...

Navin points out that epithelial cells, which line and cover the inside and outside of the body, are the cells that are believed to give rise to cancer. The researchers reported that a median of 3 ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

epithelial cell death and activation of proinflammatory pathways, which gives rise to the clinical entity known as ventilator-induced lung injury (VILI).

Merck hasn’t had much luck pairing cancer superstar Keytruda with PARP inhibitor Lynparza. | Merck hasn’t had much luck ...

Acute lung injury; CINC: Cytokine-induced neutrophil chemoattractant; CXCR: CXC chemokine receptor; ENA: Epithelial cell-derived neutrophil-activating peptide; GRO-α: Growth-related protein-α.

Merck MRK announced that its phase III KEYLYNK-001 study, evaluating its blockbuster anti-PD-1 therapy Keytruda regimen in ...