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生物通
26 天
间充质干细胞通过 CCL2/CCR2 轴调控巨噬细胞极化及 T 细胞形成,缓解 ...
综合研究结果和讨论部分,该研究揭示了 MSCs 缓解 IPS 的重要机制,即 MSCs 通过 CCL2/CCR2 轴促进巨噬细胞向 M2 极化,进而诱导调节性 CCR2 + CD4 + T 细胞的形成,这为 IPS 的预防和治疗提供了新的理论依据和潜在的治疗靶点。不过,该研究也存在一定的局限性 ...
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