This class of drugs – called Cox-2 inhibitors – has been under close scrutiny within the medical community, to the extent that the Ministry of Health has recently issued a caution pending ...

An important factor in referring to NSAIDs as 'COX-2 selective inhibitors' or 'COX nonselective inhibitors' is that 'selective' inhibition by NSAIDs is referred to at the level of the COX proteins ...

Over the following decades more anti-inflammatory drugs were developed and therapeutic ... by NSAIDs and fuelled the development of COX-2 inhibitors designed to be devoid of gastrointestinal ...

to pharmacologically modulate COX-2 function in pathological situations without disrupting its normal function. Microsomal PGES should also be assessed as a specific drug target that may have only ...

Although the effects of anti-inflammatory drugs have been ... the discovery that COX existed in two isoforms: the constitutively expressed COX-1 and an inducible COX-2 isoform 6.

Most NSAIDs affect levels of both Cox-1 and Cox-2 enzymes. Cox-2 inhibitors only block the Cox-2 enzyme. So these drugs don't affect the prostaglandins that protect the lining of your GI tract.

Like any drug, ibuprofen comes with several side ... To protect your stomach, you could consider a COX-2 inhibitor like Celebrex because it blocks inflammation while keeping intact the ...

Lithium carbonate 300mg; scored tabs. Risk of lithium toxicity (esp. recent febrile illness, acute ingestion, volume depletion/dehydration, impaired renal function, cardiovascular disease, changes ...