CRISPR-Cas systems are prokaryotic immune systems ... Mutations of CCR5 have been linked to improved outcome to HIV infection. Here the authors use CRISPR-Cas9 genome editing of CCR5 in mobilized ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in ... vector populations is a key tool for reducing malaria infections. Here, the authors develop a self-limiting ...

Yet others, called base editors, change one letter of the DNA code to another. So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to ...