Delve into the expanding and diverse field of cancer vaccines with various approaches exploiting the immune system to fight ...

Fibroblastic reticular cells (FRCs) create T-cell-supportive niches within lung cancer tumors, facilitating T-cell migration, ...

ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

While targeted HER2+ cancer drugs have led to improved ... In addition to establishing the safety of the vector-transduced CAR-M cells administered intravenously, the phase 1 study will ...

Cancer immunotherapy relies on modified ... T cells from the patient through apheresis and using a viral vector to modify the ...

Non-human adenoviruses have been used as vectors to avoid pre-existing immunity, but may still elicit a vector ... cancer that include biologics such as high-affinity natural killer cells ...

The cells were transduced with a lentiviral vector delivering the gene encoding the anti-sickling beta globin HbAS3 protein. The investigators showed that lentiviral transduction was enhanced by ...

The agency is also evaluating if there's a need for further regulatory action based on reports of hematologic malignancies from clinical trials of the therapy.