“By providing assays for those markers, we hope to help scientists understand the fitness of CAR-T cells for their intended therapeutic purpose.” For CAR-T cells and other ...

Here we have designed a CAR, CD4CAR, which redirects the ... and primary CD4+ PTCL patient samples in co-culture assays. Notably, CD4CAR T cells maintained a central memory stem cell-like ...

After injection, the CAR-T cells got to work, multiplying and seeking out the target B cells, including the pathogenic ones underlying the autoimmune conditions. This persisted for a few weeks ...

The trial will test four dose levels and include up to 18 patients with advanced, FLT3-expressing acute myeloid leukemia.

Chimeric antigen receptor (CAR) T-cell therapy has shown efficacy in blood cancers — with six CAR T-cell products now approved by the US Food and Drug Administration (FDA) to treat six ...

Culver City, California Saturday, March 1, 2025, 17:00 Hrs [IST] ...

Allogene Therapeutics expands collaboration with Foresight Diagnostics to advance development activities in Europe, UK, Canada & Australia: South San Francisco, California Thursda ...