Usually gonorrhoea is easily cured with an antibiotic called ceftriaxone. Over the last few years, however, experts have noticed a rise in the number of cases proving resistant to it. As ...

Research has also delved into the molecular mechanisms of drug resistance, identifying specific genetic mutations that confer resistance to beta-lactam antibiotics, including ceftriaxone.

Ceftriaxone, given as a single intramuscular injection, has become the last available recommended treatment for gonorrhoea globally. Zoliflodacin was originally developed by AstraZeneca and its ...

Research at the WHO Collaborating Centre for Gonorrhoea and other STIs is supported ... to develop resistance to the extended-spectrum cephalosporin ceftriaxone, the last remaining option for ...

Recent reports of outbreaks of ceftriaxone-resistant “super gonorrhoea” have heightened ... The compound uses a unique and novel mechanism of action to target the FabI enzyme, on which N.

GSK has reported topline results from a phase 3 trial of its novel antibiotic gepotidacin that could spell the end of a decades-long drought in new oral therapies for gonorrhoea. In the EAGLE-1 ...

Antibiotic-resistant gonorrhoea cases in England are on the rise and could spread more widely, health officials have warned. A new alert has been sent about ceftriaxone-resistant gonorrhoea after ...