接下来研究人员测试了干预IgG改善肥胖中代谢功能障碍的可能性。考虑到通过干预B细胞途径可能会影响抗体的产生,造成免疫缺陷,研究人员基于上述发现FcRn回收介导的堆积机制,巧妙通过靶向FcRn来避免IgG的过度堆积,而不损伤其产生过程。在巨噬细胞中敲除 ...
Cell Metabolism, launched in January 2005, is one of the newer titles in the Cell Press family. The journal focuses on physiology, with an emphasis on understanding the molecular basis of how the ...
For example, glucose metabolism affects the progression of diseases like cancer, says Kenan Moss, a specialist in cell and gene therapy at PHC Corporation of North America, a subsidiary of Japan ...
Researchers at the University of Leipzig and ETH Zurich have used single-cell sequencing to identify differences between fat ...
All cells produce substances that are essential for them to function properly. For example, in plants, specific metabolic pathways can produce glucose and chlorophyll. Metabolic pathways can be ...
Laboratory studies uncover a simple yet promising approach to enhance personalized cell therapy. A dietary supplement may ...
Scientists have identified the molecular changes that occur in the brains of aging mice and located a hot spot where much of that damage is centralized. The cells in the area are also connected with ...
Announcing a new publication for Acta Materia Medica journal. Fatty acid (FA) reprogramming has a significant role in liver cancer. However, the contribution of FA metabolism reprogramming to the ...
In contrast to EF-P, however, this protein reacts to the metabolism of the cell and adapts protein synthesis to the prevailing requirements through specific chemical modifications. "EfpL offers us ...
an energy molecule made by the mitochondria that fuels cell metabolism. "Down the line, a better understanding of protein-lipid interactions could help researchers find new therapeutic targets for ...