This article was originally published with the title “ Cellular Factors in Genetic Transformation ” in Scientific American Magazine Vol. 220 No. 1 (January 1969), p. 38 doi:10.1038 ...
This field of tumor virology was instrumental in developing the "cellular transformation assay" still used today to assess tumor growth. How do transformed cells grow? First, they no longer ...
For example, in other studies examining adenoviruses (also called DNA tumor viruses), investigators showed that cellular transformation was facilitated by stabilizing specific proteins that might ...
have shown that the presence of these protein clumps activates cellular recycling pathways in these cells, turning them into protein clearing machines. The transformation appears to be mediated by ...