Our ongoing studies have focused on identifying and characterizing inhibitors of cGAS and STING as therapeutic agents. cGAMP contains a 2’-5’ linkage. cGAMP was shown by the Zhijian Chen lab to be a ...

清华大学药学院张从刚团队在Nature Reviews Immunology发表cGAS-STING信号通路的综述文章cGAS-STING信号通路是天然免疫系统的重要组成部分，它... 清华大学药学院张从刚团队在Nature Reviews Immunology发表cGAS-STING信号通路的综述文章 cGAS-STING信号通路是天然免疫系统的重要 ...

Exclusive agreement to acquire Nudge Therapeutics includes their series of cGAS inhibitors. Nudge has developed novel potent small molecule cGAS inhibitors that prevents the overproduction of Type 1 ...

Ventus Therapeutics, a clinical-stage biopharmaceutical company with two novel small-molecule programs entering Phase 2 ...

cGAS titration at 1 hour and 24 hours demonstrates the assay's oustanding signal stability. The signal stability seen here is crucial for HTS where the screen size can require significant more time.

Exclusive agreement to acquire Nudge Therapeutics includes their series of cGAS inhibitors. Nudge has developed novel potent small molecule cGAS inhibitors that prevents the overproduction of Type ...

Her extensive development experience in immunology, inflammation, and neurology will further strengthen our team as we advance VENT-03, our first-in-class cGAS inhibitor, and VENT-02, our ...

Her extensive development experience in immunology, inflammation, and neurology will further strengthen our team as we advance VENT-03, our first-in-class cGAS inhibitor, and VENT-02, our best-in ...

MAIA Biotechnology Announces Positive Efficacy Updates for Phase 2 THIO-101 Trial in Advanced Non-Small Cell Lung Cancer ...