Chondrocytes pellets were digested with a papain extraction reagent overnight at 65 °C to recover sGAGs and mixed with blyscan dye. The color intensity was measured at 656 nm on a Benchmark ...
Solute carrier family 26 member 2 (SLC26A2) is an SO42− transporter, facilitating the uptake of inorganic sulfate into cells.
The key breakthrough came with the application of FGFR3 antagonists, BGJ398 (infigratinib) and BMN111 (vosoritide), which successfully restored bone repair in the Hch mouse model. These treatments not ...