The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

The most obvious difference between interphase and mitosis involves the appearance of a cell's chromosomes. During interphase, individual chromosomes are not visible, and the chromatin appears ...

outside their traditional habitat of chromatin in the nucleus. We are investigating the function of these epigenetic modifiers on microtubule and actin dynamics during mitosis and during quiescence, ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...