The structural and biochemical basis for E2-dependent protein conjugation was uncovered by analysis of a complex between human Ubc9 and RanGAP1. These studies revealed structural determinants for ...

Screening cell populations for high producing clones is a key rate-limiting step in the production of protein therapeutics. The Genetix ClonePix FL provides a powerful way to find and collect the ...

Antibody-drug conjugates (ADCs) can be described as highly targeted biopharmaceutical drugs that integrate monoclonal antibodies specific to surface antigens and highly potent anti-cancer agents ...

A recent study has introduced a novel class of antibody-drug conjugates (ADCs) targeting trophoblast cell surface antigen 2 (TROP2), a protein overexpressed in pancreatic ductal adenocarcinoma (PDAC), ...

This is frequently done by flow cytometry, with the help of protein L, anti-Fab antibodies or target antigens as detection methods. Of these regular options, target antigens are largely regarded ...