Of the seven identified mammalian small HSPs, only αB-crystallin ... cell–cell contacts enforce the formation of large oligomers, whatever the phosphorylation state of the protein.

They found that 72% (13 out of 18) of mutations linked to cataract formation destabilise crystallin ... protein stability was discovered by introducing mutated protein domains into yeast cells.

A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say.

They found that 72% (13 out of 18) of mutations linked to cataract formation destabilize crystallin ... protein stability was discovered by introducing mutated protein domains into yeast cells.