为探索神经系统溶酶体贮积病（LSDs）治疗策略，加拿大 CHU Ste-Justine 研究中心的研究人员开展组织蛋白酶 B（CTSB）对 LSDs 影响的研究，发现抑制 CTSB 可改善疾病症状，为相关疾病治疗提供新方向。 神经系统溶酶体贮积病（LSDs）是一类因溶酶体功能障碍引发的 ...

The company, in a filing with Bursa Malaysia yesterday, said it would pay a total of RM193mil to MISC Bhd for the 45% stake in Centralised Terminals Sdn Bhd (CTSB) it did not already own.

Mechanistically, Mtb Mce3C can bind host cathepsin B (CTSB), a lysosome-derived non-caspase protease that determines cell modalities. This binding inhibits CTSB's protease activity towards BH3 ...