The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins ... to environmental or metabolic cues and affect gene ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

Ribonucleic acid (RNA) is a linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared ...

the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a 20-DNA-letter long sequence that matches part of the guide RNA sequence.

Adenine and guanine, the two most common purines in DNA and RNA, share this core structure ... (guanosine triphosphate), which is involved in cellular signaling and protein synthesis. In addition to ...

Non-Watson-Crick base pairs can play important roles in RNA secondary structure, protein-nucleic acid interactions, and genetic recoding events. The Role of Base Pairs in Genetics Base pairs play a ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, ...

The TDP-43 RNA-binding protein is found in abnormal cytoplasmic inclusions in affected motor neurons in almost all ALS cases, and mutations in the TDP-43 gene (TARDBP) cause a rare form of familial ...