Current genetic strategies such as the one-hybrid assay 1 and phage-display techniques 2 suffer from the inability to detect proteins whose specific binding to a DNA element is dependent upon ...

DNA-binding domain (DBD) complexed with DNA reveals a protein–DNA interface with few direct major groove contacts and a number of phosphate backbone contacts that are primarily water-mediated ...

"Using the model plant Arabidopsis thaliana, we have now been able to show that in addition, so-called DNA-binding regions, located next to the already known motifs of the proteins, are needed ...

"Using the model plant Arabidopsis thaliana, we have now been able to show that in addition, so-called DNA-binding regions, located next to the already known motifs of the proteins, are needed ...

This result suggests that the protein segments unique to the much larger DNA ligase I are not essential for yeast cell growth ... Within the NTase domain is an adenylate binding pocket composed of the ...

They dock precisely onto the centromeric DNA, analogous to the "lock and key principle." However, already-known sections of the two proteins, so-called CENPC-k/CENPC motifs, are insufficient to ...

Reconstituting SUMO conjugation in vitro revealed distinct motifs in the E2 required for substrate binding and SUMO modification ... In many instances, the Ub/Ubl-modified protein is specifically ...