The basic pattern of genomic DNA methylation is established at the time of embryo implantation through a wave of de novo methylation, but CpG islands are protected through a mechanism that ...
Despite progress in aging research, many epigenetic aging clocks still rely on simple linear models using CpG DNA methylation data, often overlooking sequence context and complex interactions.
beds.ac.uk Background Epigenetics is the study of processes—beyond DNA sequence alteration—producing heritable characteristics. For example, DNA methylation modifies gene expression without altering ...